The UCI Anti-do♏ping commission has reported that all urine and blood samples taken during the Tour up to July 9, 2005, have been analysed by 𓃲the Châtenay-Malabry laboratory. There have been no infringements to the UCI anti-doping regulations, nor on the 2005 prohibited list.

Despite this, there have been two riders who have been ejected from the Tour for doping/health reasons. Evgeni Petrov (Lampre) had a high hematocrit before stage 10 and was prevented from starting, while Dario Frigo was taken away by police before stage 11, after his wife Susanna was found with a quantity of EPO and HGH in her car. Allegedly, she initially argued that the drugs were for Botox treatment, but after s𒉰he was plac🧔ed in police custody and interrogated for two days, she admitted that the drugs were for Dario.